J. Orthod.
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British Journal of Orthodontics, Vol 25, 175-178, Copyright © 1998 by British Orthodontic Society

ARTICLES

Hypodontia: genotype or environment? A case report of monozygotic twins

JD Kindelan, G Rysiecki and WP Childs
Orthodontic Department, Leeds Dental Institute, UK.

A case report is presented of monozygotic twins with variable expression of hypodontia. DNA fingerprinting was used to confirm monozygosity, and this evidence supports the theory that genetic coding is not the sole controlling factor in tooth agenesis. It is suggested that DNA fingerprinting should be considered the gold standard for determination of monozygosity.




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Copyright © 1998 British Orthodontic Society.