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Scientific Section |
1 Hard Tissue Research Group, University of Glasgow Dental School, Glasgow, UK
2 Unit of Orthodontics, University of Glasgow Dental School, Glasgow, UK
Dr S. L. Creanor, Hard Tissue Research Laboratory, University of Glasgow Dental School, 378 Sauchiehall Street, Glasgow G2 3JZ, UK (s.creanor{at}dental.gla.ac.uk).
Abstract
Objective: The ability of an experimental coating, Odyssey, to prevent demineralisation ex vivo was compared with that of a fluoride varnish, Duraphat® and a chlorhexidine-containing varnish, Cervitec.
Design: an ex vivo single-blind study.
Setting: Hard tissue research laboratory.
Materials and methods: thirty bovine enamel blocks 05 cm x 15 cm were divided into 6 groups of 5 specimens. The enamel blocks were then allocated to one of 6 surface treatments.
Interventions: (1) surface left unprepared (control), (2) Duraphat® application, (3) Cervitec application, (4) experimental polymer coating, (5) enamel conditioned with 10% citric acid and coated with the experimental polymer coating Odyssey (O + C), (6) enamel etched for 30 sec with 37% phosphoric acid and coated with the experimental coating (O + E). All specimens were cycled for 7 days through a daily procedure of demineralisation for 4 hours and remineralisation for 20 hours, and exposed to an equivalent of 2 months toothbrushing. A single operator blinded to the treatment allocation of each specimen carried artificial lesion depth assessment out using computer-assisted transverse microradiography.
Results: The control group had the greatest mean lesion depth (9716 + 298 µm) with the Duraphat® group exhibiting the lowest mean lesion depth (2453 + 1544 µm). The Duraphat®, Odyssey, O + C and O + E groups all had significantly less lesion depth when compared with no surface preparation (p < 005 for all comparisons). There were no significant differences between any of the Odyssey groups.
Conclusions: The efficacy of Duraphat® application in preventing demineralisation ex vivo has been demonstrated in the present study, but clinical trials are required to assess its usefulness in orthodontic practice.
Key words: Demineralisation, Ex vivo, Polymeric Coating, Varnish
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